Objective: to describe the severity of adverse medicine reactions as a factor in hospital admission of older patients.

Objective: to describe the severity of adverse medicine reactions as a factor in hospital admission of older patients, and to identify risk indicators for unrelenting adverse drug reactions in these patients. Design: observational cross-sectional investigation Setting: Five wards in a university hospital in the Netherlands. Subjects: patients aged 70 and throughout admitted to general medical wards. Methods: use of statistical comparison and Kramer's algorithm. Results: a strict adverse drug reaction was not past nor future in 25 (24%) of 106 patients. Thirteen patients (12%; 95% confidence interval 61-186%) were admitted probably because of an adverse mix with drugs reaction. Risk indicators for a rigid adverse drug reaction were a fall before admission (odd ratio 513 P = 0006) gastrointestinal bleeding or haematuria (odd ratio 198 P < 0001) and the use of three or more physics (odds ratio 9.8, P = 004) Conclusion: adverse physic reactions are an important cause of hospital admissions in older the community A fall before admission may indicate a strait-laced adverse drug reaction.

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