Maintenance and repair processe are crucial to the pathogenesis of ageing and late-onset disease.
Maintenance and repair processe are crucial to the pathogenesis of ageing and late-onset disease. Thus, there is increasing recognition of the importance of genetic factors in the disentanglement of late-onset conditions such as calamity Parkinson's disease and osteoporosis, and accumulating evidence for a genetic component part in the development of chronic obstructive pulmonary disease. We review the approaches and point in disputes in the genetic investigation of manifold disorders in old age, taking chronic obstructive pulmonary disease as an example.